Cell Survival and Cell Death Eric H. Baehrecke

ISBN: 9781936113316

Published: August 31st 2013

Hardcover

380 pages


Description

Cell Survival and Cell Death  by  Eric H. Baehrecke

Cell Survival and Cell Death by Eric H. Baehrecke
August 31st 2013 | Hardcover | PDF, EPUB, FB2, DjVu, talking book, mp3, ZIP | 380 pages | ISBN: 9781936113316 | 8.16 Mb

Billions of cells die every day in the human body. This is required for normal development and physiology, as well as the elimination of errant cells. Apoptosis and other cell death mechanisms are complex and carefully controlled. If cell death doesMoreBillions of cells die every day in the human body. This is required for normal development and physiology, as well as the elimination of errant cells.

Apoptosis and other cell death mechanisms are complex and carefully controlled. If cell death does not occur when it should, cancer and other diseases may develop. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology covers all aspects of apoptosis, autophagy, and necrosis. Contributors describe in detail the molecular mechanisms of cell death signaling, including death receptor-ligand systems, BCL-2 family proteins, mitochondrial permeabilization, the endocytic pathway, caspases, and signals that trigger the clearance of dying cells.

Survival mechanisms and proteins such as IAPs that antagonize cell death are also described. This volume includes discussion of tumor suppression, the altered metabolism of cancer cells, and the development of therapeutic drugs. It is an essential reference for cell and developmental biologists, cancer biologists, and all who want to understand when and how cell death is required for life.



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